Johnna Temenoff completed her Ph.D. in 2003 from Rice University, after graduating from Case Western Reserve University in 1998 with a B.S. in Biomedical Engineering and a B.A. in French. Her thesis work, completed under the guidance of Dr. A. G. Mikos, centered on development of a novel injectable poly(ethylene glycol)-based hydrogel material for bone and cartilage tissue engineering. Johnna chose to remain at Rice 2003-2005 to co-author an undergraduate biomaterials textbook with Dr. Mikos. The result, Biomaterials: The Intersection of Biology and Materials Science, published in 2008 by Pearson-Prentice Hall, has been adopted by over 40 universities in the U.S. and has been published in two international editions. The book was awarded the Meriam- Wiley Award for Best New Engineering Textbook by the American Society for Engineering Education in 2010. In 2005, Johnna joined the faculty of the Coulter Department of Biomedical Engineering at Georgia Tech/Emory University in Atlanta, GA, where she currently holds the position of Associate Professor. Her research in the area of novel polymeric materials for mesenchymal stem cell differentiation has resulted in over 25 publications to date and earned her an Arthritis Foundation Investigator Award in 2006 and a NSF CAREER Award in 2008.
Title of Abstract
Rotator cuff injuries represent a range of pathologies, from early tendon overuse to full thickness rotator cuff tendon tears. Increasingly, rotator cuff disease is viewed as a whole-joint pathology, but it is unclear how the various tissues involved respond at different disease stages. Our laboratory’s work has recently identified and characterized cartilage degeneration as well as tendon injury in rodent models of both overuse and full tear rotator cuff disease. Moreover, degenerative changes to the supraspinatus muscle after tendon tear were characterized in a rodent model. Based on the insights generated regarding the progression of degenerative changes within the shoulder, potential regenerative strategies for specific tissues within the joint will be outlined.
Johnna S. Temenoff
All Author Affiliations
Coulter Department of Biomedical Engineering, Georgia Tech/Emory University